The San Francisco 49 ers have actually only played one video game of the 2025 NFL period, and already they are dealing with substantial injury issues.
San Francisco’s remarkable 17 – 13 gain the Seattle Seahawks was a pyrrhic one, as tight end George Kittle experienced a hamstring injury that will certainly see him miss four weeks after he was put on injured get
Losing Kittle was a large strike on its own, yet even worse news has actually come this week concerning quarterback Brock Purdy, who is apparently readied to miss 2 to five weeks with turf toe , a sprain at the base of the ligaments of the big toe.
The 49 ers are currently set to turn to backup Mac Jones in Week 2, with the day of Purdy’s return important as San Francisco intends to stay clear of falling into an opening that swiftly reduce hopes of returning to the playoffs.
Jones is a quarterback whom several see as an ideal fit for head train Kyle Shanahan’s offensive system. The 49 ers had the opportunity to select him 3rd total in the 2021 draft, but instead went with Trey Lance in a significant misstep, with San Francisco’s blushers saved by the appearance of seventh-round pick Purdy.
Over 4 years on, Jones is now set to get his opportunity to play for Shanahan in a regular-season video game, but there’s no question he will certainly be a downgrade from Purdy, making a possible five-game absence a huge obstacle for San Francisco to get over.
Here’s a consider the games Purdy might miss out on.
Week 2: @ New Orleans Saints
Purdy is set to be a viewer for the most workable video game of the stretch, with the 49 ers checking out a Saints team many view as the faves for the number one general pick in next year’s draft.
The Superdome is an imposing and really loud field, and the Saints hung difficult against the Arizona Cardinals recently, only losing 20 – 13
Still, the 49 ers will likely be certain of their defense bring the tons against quarterback Spencer Rattler and moving to 2 -0. With the games that adhere to, there’s a debate to be made that, if Purdy is out for a complete 5 weeks, their success in preventing an upset in this one can make or damage the 49 ers’ period.
Week 3: vs. Arizona Cardinals
This is where things start to get tougher.
The Cardinals are by no implies a juggernaut, however they are a team rising and won this very same fixture last season many thanks to a fourth-quarter return.
Kyler Murray is a quarterback from whom his unquestionably lofty ceiling always appears contemporary of reach, but he has continually confounded the 49 ers with his dual-threat ability. Beyond of the round, the Cardinals have the defensive ability to make it a long afternoon for Mac Jones if Purdy does without a doubt miss San Francisco’s home opener at Levi’s Arena.
Week 4: vs. Jacksonville Jaguars
Need to Purdy return for this match, the 49 ers will certainly be expected to prevail.
The 49 ers have actually dominated current games with the Jaguars, most recently squashing them on the road en path to an appearance in Super Dish 58 in the 2023 period.
But a Purdy absence would make a conference with Trevor Lawrence, for whom Jones acted as the backup last year, substantially harder.
The Jags have a sharp offending mind at head train in Liam Coen that is wishing to evoke elite degree quarterback play from previous primary pick Lawrence, and are blessed with significant young skill on the offensive side of the round.
There’s additionally the retribution video game story at play below, with previous San Francisco defensive deal with Arik Armstead intending to make the 49 ers spend for parting company with him in 2015 complying with an agreement conflict.
Week 5: at Los Angeles Rams
After the Jaguars game, the 49 ers deal with a brief week as they make the journey southern to encounter their in-state competitors on Thursday Night Football.
It has actually ended up being the standard for 49 ers fans to pack out SoFi Arena for this video game, with the home of the Rams happening referred to as ‘Levi’s South’ by San Francisco fans.
However the 49 ers saw their prominence of this rivalry interrupted last period as the Rams brushed up the collection, winning at home with a remarkable fourth-quarter comeback. If Purdy is still unavailable, after that it will certainly be extremely hard to see the Niners dominating in what will certainly be Kittle’s last game on the sidelines.
Week 6: at Tampa Bay Bay Buccaneers
The advantage of using a short week is the extensive rest in advance of the succeeding video game, and the 49 ers will certainly be hoping that plays a role in them videotaping one more win in Tampa, having actually come via a thriller versus Baker Mayfield and Co. last season.
Tampa fl Bay, however, has a packed offense and a defense boasting talent at every level. The cross-country trip would be incredibly difficult even with Purdy back in the battle royal. Encountering the Bucs when traveling with Jones at quarterback would be a recipe for a miserable journey.